Dietary Guidelines and its Implications for Coconut Oil
Fabian M. Dayrit*
Department of Chemistry, Ateneo de Manila University, Katipunan Ave.,
Loyola Heights, Quezon City, Philippines
*Corresponding author: This email address is being protected from spambots. You need JavaScript enabled to view it.
ABSTRACT
The dietary advice that is generally followed nationally and internationally closely follows the Dietary Guidelines for Americans which was first published in 1980 and which has been through eight editions. All of the editions of the Dietary Guidelines recommend a diet that is low in fat, and most editions recommend the replacement of saturated fat with polyunsaturated fat. This recommendation is based on the saturated fat-cholesterol-heart disease hypothesis that was first proposed by Ancel Keys in the 1950s. Coconut oil was labeled as unhealthy because of its high saturated fat composition. However, this label is unwarranted. Re-analysis of the work that Keys undertook reveals that he used some inappropriate assumptions that invalidate his hypothesis. Keys undertook a large controlled feeding study, called the Minnesota Coronary Survey (MCS), to prove his hypothesis but he did not publish the results of this work. A recent re-analysis of this work has shown that his results do not support his hypothesis. Further, historical documentary evidence has revealed the significant involvement of the American sugar industry in influencing dietary policy by blaming saturated fat for heart disease. Populations that have adhered to the low-saturated fat dietary recommendation have become significantly overweight and obese. In contrast, populations that continue to follow their traditional diet which includes coconut have not had high rates of obesity. The Keys hypothesis needs to be abandoned. . . . . read more
INTRODUCTION
In 1980, the U.S. Departments of Agriculture, and Health and Human Services published the first edition of the Dietary Guidelines for Americans to serve as the basis for U.S. federal food and nutrition education programs. Despite almost four decades and eight editions of the Dietary Guidelines, heart disease and obesity have remained major health concerns in the US. Cancer has crept up in the list of non-communicable diseases (NCI 2017) and Alzheimer’s disease, which is still untreatable, is already exacting significant financial and social costs (Alzheimer’s Association 2017).
REFERENCES
Alzheimer’s Association. 2017. Alzheimer’s disease facts and figures. Retrieved from http://www.alz.org/documents_custom/2017-facts-and-figures.pdf on 27 March 2017.
Assunção ML, Ferreira HS, dos Santos AF, Cabral CR Jr, Florêncio TM. 2009. Effects of dietary coconut oil on the biochemical and anthropometric profiles of women presenting abdominal obesity. Lipids 44(7):593-601.
Bach AC, Babayan VK. 1982. Medium-chain triglycerides: an update. Am J Clin Nutr 36: 950-962.
Bray GA, Nielsen SJ, Popkin BM. 2004. Consumption of high-fructose corn syrup in beverages may play a role in the epidemic of obesity. Am J Clin Nutr 79: 537-543.
Codex Alimentarius. 2015. Standard for named vegetable oils, Codex Stan 210-1999, amended 2015. Food and Agriculture Organization and World Health Organization.
Cohen E, Cragg M, de Fonseka J, Hite A, Rosenberg M, Zhou B. 2015. Statistical review of US macronutrient consumption data, 1965-2011: Americans have been following dietary guidelines, coincident with the rise in obesity. Nutrition 31:727-732.
Daniel CR, Cross AJ, Koebnick C, Sinha R. 2011. Trends in meat consumption in the United States. Public Health Nutr 14(4):575-583.
Deol P, Evans JR, Dhahbi J, Chellappa K, Han DS, Spindler S, SLADEK FM. 2015. Soybean oil is more obesogenic and diabetogenic than coconut oil and fructose in mouse: Potential role for the liver. PLoS ONE 10(7):e0132672.
de Vos LC, Lefrandt JD, Dullaart RPF, Zeebregts CJ, Smit AJ. 2016. Advanced glycation end products: An emerging biomarker for adverse outcome in patients with peripheral artery disease. Atherosclerosis 254: 305-313.
Dwyer JT, Ausman L, Kennedy E. 2010. D. Mark Hegsted, Ph.D. (Biographical Article). J Nutr 140(8): 1402-1403.
Florentino RF, Aguinaldo AR. 1987. Diet and cardiovascular disease in the Philippines. Philipp J Coconut Studies 13(2): 56-70.
[FAO] Food and Agriculture Organization. 2008. Fats and Fatty Acids in Human Nutrition. Report of an Expert Consultation. p.9.
Frantz ID Jr., Dawson EA, Ashman PL, Gatewood LC, Bartsch GE, Kuba K, Elizabeth R. Brewer ER. 1989. Arteriosclerosis 9:129-135.
Galanis DJ, McGarvey ST, Quested C, Sio B, Afele-Fa'Amuli S. 1999. Dietary intake of modernizing Samoans: Implications for risk of cardiovascular disease. J Amer Dietetic Assoc 99(2):184-190.
Goldin A, Beckman JA, Schmidt AM, Creager MA. 2006. Advanced glycation end products. Sparking the development of diabetic vascular injury. Circulation 114:597-605.
Goran MI, Ulijaszek SJ, Ventura EE. 2012. High fructose corn syrup and diabetes prevalence: A global perspective. Global Public Health 1-10.
Hegab Z, Gibbons S, Neyses L, Mamas MA. 2012. Role of advanced glycation end products in cardiovascular disease. World J Cardiol 4(4):90-102.
Hegsted DM, McGandy RB, Myers ML, Stare FJ. 1965. Quantitative effects of dietary fat on serum cholesterol in man. Am J Clin Nutr 17(5):281-295.
Hegsted DM. 2004. Fredrick John Stare (1910-2002) (Biographical Article). J. Nutr 134: 1007-1009.
Index Mundi. 2016. http:// www.indexmundi.com/
Johnston PV. 1957. Occurrence of trans fatty acids in human tissue. Science 126(3276): 698-699.
Kearns CE, Schmidt LA, Glantz SA. 2016. Sugar industry and coronary heart disease research. A historical analysis of internal industry documents. JAMA Intern Med E1-E6.
Keys A. 1952. The age trend of serum concentrations of cholesterol and of Sf 10-20 (“G”) substances in Adults. J Gerontol 7(2): 201-206.
Keys A. 1955. Atherosclerosis and the diet. S.A. Med J 332-334.
Keys A, Anderson JT, Grande F. 1957a. Prediction of serum-cholesterol responses of man to changes in fats in the diet. Lancet 959-965.
Keys A, Buzina R, Grande F, Anderson JT. 1957b. Effects of meals of different fats on blood coagulation. Circulation 15:274-279.
Keys A. 1957c. Epidemiologic aspects of coronary artery disease (editorial). J Chron Dis 6(5): 552-559.
Keys A, Parlin RW. 1966. The Serum Cholesterol Response to Changes in Dietary Lipids. Am J Clin Nutr 19:175-181.
Keys A, Menotti A, Karvonen MJ, ARAVANIS C, BLACKBURN H, BUZINA R, DJORDJEVIC BS, DONTAS AS, FIDANZA F, KEYS MH, et al. 1986. The diet and 15-year death rate in the Seven Countries Study. Am J Epidemiol 124(6):903-915.
KEYS A. 1971. Sucrose in the diet and coronary heart disease. Atherosclerosis 14(2):193–202.
Ko S-Y, Ko H-A, Chu K-H, Shieh T-M, Chi T-C, Chen H-I, CHANG W-C, CHANG S-S. 2015. The possible mechanism of Advanced Glycation End Products (AGEs) for Alzheimer’s disease. PLoS ONE 10(11):e0143345.
Kris-Etherton PM. 2010. Trans-fat and coronary heart disease. Crit Rev Food Sci Nutr 50:29-30.
Kritchevsky D, Moyer AW, Tesar WC, Logan JB, Brown RA, Davies MC, Cox HR. 1954. Effect of cholesterol vehicle in experimental atherosclerosis. Am J Physiol 178:30-32.
Lawrence GD, Mavi A, Meral K. 2008. Promotion by phosphate of Fe(III)- and Cu(II)-catalyzed autoxidation of fructose. Carbohydrate Res 343(4):626-635.
Liu T-X, Niu H-T, Zhang S-Y. 2015. Intestinal microbiota metabolism and atherosclerosis. Chin Med J 128(20):2805-2811.
Matthan NR, Ausman LM, Lichtenstein AH, Jones PJH. 2000. Hydrogenated fat consumption affects cholesterol synthesis in moderately hypercholesterolemic women. J Lipid Res 41:834-839.
Mayes PA. 1993. Intermediary metabolism of fructose. Am J Clin Nutr 58(suppl): 754S-765S.
McGandy RB, Hegsted DM, Stare FJ. 1967a. Dietary fats, carbohydrates and atherosclerotic vascular disease. NEJM 277(4): 186-192.
McGandy RB, Hegsted DM, Stare FJ. 1967b. Dietary fats, carbohydrates and atherosclerotic vascular disease (Concluded). NEJM 277(5):242-247.
Mensink RP, Katan MB. 1990. Effect of dietary trans fatty acids on high-density and low-density lipoprotein cholesterol levels in healthy subjects. NEJM 323(7):439-445.
[NCI] National Cancer Institute. 2017. Cancer statistics. https://www.cancer.gov/about-cancer/understanding/statistics.
[NIDDK] National Institute of Diabetes and Digestive and Kidney Diseases. 2012. Trends in overweight and obesity among adults, United States, 1962-2010. Retrieved from https://www.niddk.nih.gov/health-information/health-statistics/Pages/overweight-obesity-statistics.aspx on 25 March 2017.
Ng CH, Yao XQ, Huang Y, Chen Z-Y. 2008. Oxidised cholesterol is more hypercholesterolaemic and atherogenic than non-oxidised cholesterol in hamsters. Br J Nutr 99(4):749-755.
O'Connor A. 2016. A decades-old study, rediscovered, challenges advice on saturated fat. New York Times, April 13, 2016. http://well.blogs.nytimes.com/2016/04/13/a-decades-old-study-rediscovered-challenges-advice-on-saturated-fat/?_r=0.
Page IH, Allen EV, Chamberlain FL, Keys A, Stamler J, Stare FJ. 1961. Dietary fat and its relation to heart attacks and strokes. Report by the Central Committee for Medical and Community Program of the American Heart Association. Circulation 23:133-136.
Prior IA, Davidson F, Salmond CE, Czochanska Z. 1981. Cholesterol, coconuts, and diet on Polynesian atolls: a natural experiment: the Pukapuka and Tokelau Island studies. Am J Clin Nutr 34:1552-1561.
Ramsden CE, Zamora D, Majchrzak-Hong S, Faurot KR, Broste SK, Frantz RP, Davis JM, Ringel A, Suchindran CM, Hibbeln JR. 2016. Re-evaluation of the traditional diet-heart hypothesis: analysis of recovered data from Minnesota Coronary Experiment (1968-73). BMJ 353:i1246.
Scrimshaw NS. 2014. D. Mark Hegsted 1914-2009. National Academy of Sciences Biographical Memoirs. http://www.nasonline.org/memoirs.
Simopoulos AP. 2002. The importance of the ratio of omega-6/omega-3 essential fatty acids. Biomed Pharmacother 56(8):365-379.
Simopoulos AP. 2008. The importance of the omega-6/omega-3 fatty acid ratio in cardiovascular disease and other chronic diseases. Exp Biol Med 233(6):674-688.
Simopoulos AP. 2010. Genetic variants in the metabolism of omega-6 and omega-3 fatty acids: their role in the determination of nutritional requirements and chronic disease risk. Exp Biol Med 235: 785-795.
Sun SZ, Empie MW. 2012. Fructose metabolism in humans – what isotopic tracer studies tell us. Nutr Metab 9:89.
[USDA] U.S. Department of Agriculture, Economic Research Service. 2014. ERS Oilseed Yearbook.
[WHO] World Health Organization. 2003. Diet Food Supply and Obesity in the Pacific. https://apps.who.int/infobase/Comparisons.aspx.
[WHO] World Health Organization. 2015. Healthy diet Fact sheet No. 394. http://www.who.int/mediacentre/factsheets/fs394/en/.
Yerushalmy J, Hilleboe HE. 1957. Fat in the diet and mortality from heart disease; a methodologic note. NY State J Med 57(14): 2343-2354.
Yudkin J. 1965. Letter to the editor, BMJ 874.