Regenerable Antimicrobial Polyurethane Coating Based on N-Hydroxymethylated Hydantoin
Wilfredo Bisquera Jr. and Florentino C. Sumera1*
Material Science and Engineering Program, College of Science,
University of the Philippines, Diliman, Quezon City
1Institute of Chemistry, University of the Philippines, Diliman, Quezon City
corresponding author: This email address is being protected from spambots. You need JavaScript enabled to view it./willie_bisquera@yahoo.com
ABSTRACT
Polyurethane coating made from castor oil and toluene diisocyanate was transformed into an antimicrobial coating by covalently attaching monomethylol hydantoin, a potential N-halamine derivative with regenerable antimicrobial properties. The coating was readily converted to N-halamine structures on exposure to a halogen source such as commercially available sodium hypochlorite. Once chlorinated, the coating became biocidal against representative organisms such as Staphylococcus aureus (gram positive), Escherichia coli (gram negative), and Candida Albicans. The coating could be recharged repeatedly and become antimicrobial for at least five days by reapplication of the hypochlorite solution. The surface morphology, thermal and spectral properties of the coating were analyzed by SEM, contact angle, DSC, TGA, FTIR before and after chlorination. Chlorine content was determined by titration using iodometric method. The structures of the starting hydantoin derivatives were characterized by FTIR, and H1 NMR.
INTRODUCTION
Due to wide spread proliferation of infectious pathogens and persistence of microorganisms on surfaces, antimicrobial polymers have attracted considerable interests. Biocidal polymers may be categorized by their mode of antimicrobial activity: biocide release or contact-kill (Grunzinger et al. 2007). . . . . . . .
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